A fictional dataset used to showcase group-based clinical significance analyses and analyses with many participants.
Format
A tibble with 1140 rows and 4 variables:
patientPatient identifier
conditionExperimental condition
measurementIndicator of measurement
mom_diMind over Mood Depression inventory scores (lower is better)
Details
In a fictional clinical trial, the effectiveness of a new antidepressant should be examined and depressed patients were randomized to one of four groups:
A wait list control group that did not receive a medication
An inactive placebo group, i.e., a group that received a placebo (inert substance without proposed clinical effect) pill
An active placebo group, i.e., a group that received a placebo that evokes side effects like mild nausea or a dry mouth
The antidepressant group, so the target medication of this trial that should have a clinical impact on the patients' depressive symptoms
Suppose they underwent outpatient treatment, depressive symptoms were measured before and after treatment with the Mind over Mood Depression Inventory (MoM-DI) by Greenberger & Padesky (2015), and if a patient received a pill, the clinician and the patient did not know, what type of medicaction they consumed.
Further, the minimal important difference for an improvement as measured by this instrument was agreed to be an 8 point decrease. A deterioration can be assumed if instrument scores increased by 5 points.
The functional population (i.e., non-depressed individuals) can be expected to have a mean score of M = 8 points with a standard deviation of SD = 7.